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ADHD Medication During Pregnancy and Breastfeeding The decision to stop or keep ADHD medications during pregnancy and breastfeeding is challenging for women with the condition. There are few data on how exposure to ADHD for a long time could affect a foetus. adhd depression medication published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological problems like hearing loss or vision, febrile seizures, or IQ impairment. The authors acknowledge that more high-quality research is needed. Risk/Benefit Analysis Women who are expecting and taking ADHD medication need to evaluate the benefits of using it against the potential risks to the baby. The doctors don't have the information to provide clear recommendations, but can provide information on risks and benefits to aid pregnant women in making an informed decision. A study published in Molecular Psychiatry concluded that women who were taking ADHD medication in early pregnancy were not at greater risk of fetal malformations or structural birth defects. Researchers conducted a large population-based case-control study to evaluate the incidence of major structural birth defects in babies born to mothers who had taken stimulants during early pregnancy, as well as those who had not. Clinical geneticists, pediatric cardiologists and other experts looked over the cases to make sure that the classification was correct and to reduce any bias. However, the researchers' study was not without its flaws. Most important, they were unable to separate the effects of the medication from the effects of the disorder at hand. This limitation makes it difficult to determine whether the small differences observed in the exposed groups are due to medication use or the confounding effect of comorbidities. The researchers did not examine the long-term effects for the offspring. The study showed that infants whose mothers took ADHD medication during pregnancy had a higher chance of being admitted to the neonatal care unit (NICU) as compared to those whose mothers did not use any medication during pregnancy or had stopped taking their medication before or during pregnancy. This increase was caused by central nervous system disorders. The increased risk of admission was not affected by the stimulant medications used during pregnancy. Women who used stimulant ADHD medication during pregnancy were also at an elevated risk of having a caesarean delivery or having a baby born with a low Apgar score (less than 7). These increases appear to be independent of the type of medication taken during pregnancy. The researchers suggest that the risk of a small amount with the use of ADHD medications during early pregnancy could be offset by the greater benefit to both mother and child of continued treatment for the woman's condition. Doctors should discuss with their patients about this and, if possible, help them develop coping strategies that can lessen the impact of her disorder in her daily life and relationships. Medication Interactions As more women than ever before are being diagnosed with ADHD and treated with medication, the question of whether or not to stop treatment during pregnancy is a question that doctors are having to face. These decisions are frequently made without clear and authoritative evidence. Instead, doctors have to take into account their own experience in conjunction with the experiences of other physicians and the research on the topic. Particularly, the issue of potential risks for the baby can be a challenge. A lot of studies on this subject are based on observational evidence instead of controlled research and their findings are often contradictory. The majority of studies focus on live births, which can underestimate the severity of teratogenic effects that can lead to terminations or abortions of pregnancy. The study that is discussed in the journal club addresses these shortcomings by analyzing the data from deceased and live births. Conclusion Some studies have found an association between ADHD medications and certain birth defects however, other studies haven't found a correlation. Most studies have shown an unintended, or slight negative effect. As a result an accurate risk-benefit analysis is required in every instance. It can be challenging, if not impossible, for women suffering from ADHD to stop taking their medication. In a recent article published in Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can cause depression and feelings of isolation. A decrease in medication could affect the ability to safely drive and to perform work-related tasks which are crucial aspects of daily life for people with ADHD. She suggests that women who are not sure whether to continue taking the medication or stop it due to their pregnancy, educate their family members, coworkers, and acquaintances about the condition, the impact on daily functioning and the benefits of continuing the current treatment. Educating them can also aid in ensuring that the woman feels supported in her struggle with her decision. Certain medications can be passed through the placenta. If the patient decides to not take her ADHD medication while breastfeeding, it's important to be aware that the medication could be passed on to her infant. Risk of Birth Defects As the use and abuse of ADHD medication to treat symptoms of attention deficit disorder hyperactivity disorder (ADHD), increases the concern over the possible effects of the drugs on fetuses. A recent study published in the journal Molecular Psychiatry adds to the body of information on this topic. Researchers used two massive datasets to analyze more than 4.3 million pregnancy and determine whether stimulant medications increased the risk of birth defects. Researchers discovered that although the risk overall is low, the first trimester ADHD exposure to medication was associated with slightly higher rates of specific heart defects such as ventriculoseptal defect. The researchers behind the study found no association between early medication use and other congenital anomalies, like facial clefting, or club foot. The results are in line with previous studies showing a small but significant increase in the risk of heart malformations among women who began taking ADHD medications before the time of pregnancy. This risk increased during the latter half of pregnancy, when a lot of women stopped taking their medication. Women who took ADHD medications during the first trimester of their pregnancies were also more likely to have caesarean section, low Apgar score after delivery and a baby who required help breathing at birth. The researchers of the study were unable to eliminate bias due to selection because they restricted the study to women with no other medical conditions that could have contributed to the findings. The researchers hope their research will help inform the clinical decisions of doctors who treat pregnant women. They suggest that although discussing the risks and benefits is crucial but the decision to stop or keep treatment must be based on each woman's requirements and the severity of her ADHD symptoms. The authors caution that, although stopping the medication is an option to look into, it is not advised due to the high rate depression and other mental problems for women who are pregnant or have recently given birth. Further, research shows that women who stop taking their medications will have a harder adjustment to life without them once the baby is born. Nursing The responsibilities of being a new mom can be overwhelming. Women suffering from ADHD can face severe challenges when they have to manage their symptoms, go to doctor appointments and prepare for the birth of a baby and adjust to new routines. This is why many women decide to continue taking their ADHD medications throughout the course of pregnancy. The majority of stimulant drugs are absorbed through breast milk in small amounts, so the risk to breastfeeding infant is minimal. The amount of exposure to medications will differ based on dosage, frequency of administration and the time of day. In addition, different medications enter the baby’s system via the gastrointestinal tract or through breast milk. The impact of these medications on the health of a newborn isn't fully understood. Due to the absence of research, some physicians may recommend stopping stimulant drugs during a woman's pregnancy. adhd depression medication is a difficult decision for the woman, who must weigh the benefits of taking her medication as well as the risks to the embryo. Until more information is available, doctors should ask all pregnant patients about their experience with ADHD and whether they are planning or taking to take medication during the perinatal period. Numerous studies have demonstrated that women can continue taking their ADHD medication safely while breastfeeding and during pregnancy. This has led to more and more patients choose to do so and after consulting with their doctor, they have found that the benefits of maintaining their current medication far outweigh any risks. Women with ADHD who are planning to nurse should seek the advice of a specialist psychiatrist before becoming pregnant. They should review their medications with their physician and discuss the advantages and disadvantages of continuing treatment, including non-pharmacological strategies. Psychoeducation is also required to help pregnant women suffering from ADHD recognize the signs and the underlying disorder. They should also learn about treatment options and strengthen strategies for coping. This should include a multidisciplinary approach, which includes the GP, obstetricians and psychiatry. Counselling for pregnancy should include the discussion of a treatment plan for both mother and child, as well as monitoring for signs of deterioration, and when necessary, making adjustments to the medication regimen.
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